Human DDB1- and CUL4-associated factor 13 (DCAF13) ELISA Kit

Este producto es parte de DCAF - DDB1 and CUL4 associated factor
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715€ (96 tests)

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935106861
info@markelab.com
name
Human DDB1- and CUL4-associated factor 13 (DCAF13) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx509761
tested applications
ELISA

Description

Human DDB1- and CUL4-associated factor 13 (DCAF13) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human DDB1- and CUL4-associated factor 13 (DCAF13) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
DDB1- and CUL4-associated factor 13 (DCAF13)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q9NV06
Alias
GM83,Sof1,WDSOF1,HSPC064,WD repeat and SOF domain-containing protein 1
Background
Elisa kits for DCAF13
Status
RUO
Note
Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

DDB1 and CUL4 associated factor 13 (DCAF13) is a substrate receptor within the CUL4-DDB1 E3 ubiquitin ligase complex, playing a pivotal role in regulating protein degradation. DCAF13 contains WD40 repeats that facilitate substrate recognition and protein-protein interactions, enabling the specific targeting of proteins for ubiquitination. It has been implicated in the regulation of cellular homeostasis, particularly through its role in ubiquitination pathways that ensure proper protein turnover. DCAF13 has been associated with the control of transcriptional processes and may be involved in modulating the stability of transcription factors and other nuclear proteins. Although its specific substrates and biological roles are not fully understood, DCAF13 is thought to influence cell cycle regulation and signal transduction pathways. Its expression in various tissues suggests a broad functional relevance in maintaining cellular integrity and responding to environmental or intracellular stress signals. Further studies are needed to identify its specific targets and elucidate its contribution to E3 ligase complex functionality.

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