Human DDB1- and CUL4-associated factor 12-like protein 2 (DCAF12L2) ELISA Kit
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Human DDB1- and CUL4-associated factor 12-like protein 2 (DCAF12L2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human DDB1- and CUL4-associated factor 12-like protein 2 (DCAF12L2) concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | DDB1- and CUL4-associated factor 12-like protein 2 (DCAF12L2) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q5VW00 |
| Alias | WDR40C,WD repeat-containing protein 40C |
| Background | Elisa kits for DCAF12L2 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
DDB1 and CUL4 associated factor 12 like 2 (DCAF12L2) is another member of the DCAF12 family, characterized by WD40 repeats that are critical for interactions with the CUL4-DDB1 complex and substrate recognition. Although little is known about DCAF12L2, its expression pattern indicates potential involvement in reproductive biology, particularly in germ cells, as well as general protein homeostasis in various tissues. Evolutionary studies have revealed events such as intronization in the DCAF12L2 gene, suggesting that this paralog has developed distinct functions compared to DCAF12 and DCAF12L1. These changes may relate to specialized mechanisms of protein regulation that allow functional diversification in different cellular contexts. While further studies are required to identify its substrates and exact functions, DCAF12L2 is a promising target for investigating the regulation of ubiquitination and its impact on cellular homeostasis and protein function.
Related Products
DCAF12L2 Antibody
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by Gly-His and Trp-Asp (GH-WD), which may facilitate formation of heterotrimeric or multi-protein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene appears to represent an intronless retrocopy of a related multi-exon gene located on chromosome 9. However, the CDS of this intronless gene remains intact, it is conserved in other mammalian species, it is known to be transcribed, and it is therefore thought to encode a functional protein.
Ver Producto
Human DDB1- and CUL4-associated factor 12-like protein 2 (DCAF12L2) ELISA Kit
Human DDB1- and CUL4-associated factor 12-like protein 2 (DCAF12L2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human DDB1- and CUL4-associated factor 12-like protein 2 (DCAF12L2) concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
Ver ProductoMouse DDB1- and CUL4-associated factor 12-like protein 2 (DCAF12L2) ELISA Kit
Mouse DDB1- and CUL4-associated factor 12-like protein 2 (DCAF12L2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse DDB1- and CUL4-associated factor 12-like protein 2 concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
Ver Producto