Human Cytosolic carboxypeptidase 6 (AGBL4) ELISA Kit

Este producto es parte de AGBL-AGBL carboxypeptidase
Human Cytosolic carboxypeptidase 6 (AGBL4) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for AGBL4

proveedor

Abbexa

reference

abx505007

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Cytosolic carboxypeptidase 6 (AGBL4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Cytosolic carboxypeptidase 6 (AGBL4) concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

AGBL4 is an enzyme involved in the deglutamylation of tubulin, a critical process for regulating microtubule dynamics and stability. It removes polyglutamate side chains from the C-terminal tails of tubulin, thereby influencing microtubule-based transport, axon guidance, and neuronal plasticity. AGBL4 is expressed in various tissues, including the brain, heart, and skeletal muscle, suggesting a role in both neuronal and muscular function. Dysregulation of AGBL4 has been associated with neurological disorders, where defective tubulin modifications impair intracellular transport, leading to synaptic dysfunction and neurodegeneration. Emerging research also implicates AGBL4 in certain cancers, where altered microtubule stability can drive aberrant cell division and migration. The enzyme’s activity is crucial for maintaining the delicate balance of tubulin modifications required for normal cellular and tissue homeostasis.

Características del producto

category

ELISA Kits


immunogen target

Cytosolic carboxypeptidase 6 (AGBL4)


reactivity

Human


test range

0.156 ng/ml - 10 ng/ml


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

CCP6


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

AGBL4


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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