Human Cytosolic carboxypeptidase 6 (AGBL4) ELISA Kit
715€ (96 tests)
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name
Human Cytosolic carboxypeptidase 6 (AGBL4) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx505007
tested applications
ELISA
Description
Human Cytosolic carboxypeptidase 6 (AGBL4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Cytosolic carboxypeptidase 6 (AGBL4) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Cytosolic carboxypeptidase 6 (AGBL4) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q5VU57 |
| OMIM | 616476 |
| Alias | CCP6 |
| Background | Elisa kits for AGBL4 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
AGBL4 is an enzyme involved in the deglutamylation of tubulin, a critical process for regulating microtubule dynamics and stability. It removes polyglutamate side chains from the C-terminal tails of tubulin, thereby influencing microtubule-based transport, axon guidance, and neuronal plasticity. AGBL4 is expressed in various tissues, including the brain, heart, and skeletal muscle, suggesting a role in both neuronal and muscular function. Dysregulation of AGBL4 has been associated with neurological disorders, where defective tubulin modifications impair intracellular transport, leading to synaptic dysfunction and neurodegeneration. Emerging research also implicates AGBL4 in certain cancers, where altered microtubule stability can drive aberrant cell division and migration. The enzyme’s activity is crucial for maintaining the delicate balance of tubulin modifications required for normal cellular and tissue homeostasis.
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