Human Cytoplasmic protein NCK1 (NCK1) ELISA Kit
715€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Human Cytoplasmic protein NCK1 (NCK1) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx534659
Tested Applications
ELISA
Description
Human Cytoplasmic protein NCK1 (NCK1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Cytoplasmic protein NCK1 (NCK1) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Immunogen Target | Cytoplasmic protein NCK1 (NCK1) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P16333 |
| Gene ID | 4690 |
| OMIM | 600508 |
| Alias | NCK1, NCK, NCKalpha, nck-1, NCK adaptor protein 1 |
| Background | Elisa Kits for: NCK1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Background
NCK1 is a cytoplasmic adaptor protein containing three SH3 domains and one SH2 domain, which allows it to mediate interactions between receptor tyrosine kinases (RTKs) and downstream effectors in signaling pathways. NCK1 is involved in actin cytoskeleton reorganization, cell motility, and immune synapse formation by linking signaling proteins such as WASP, WAVE, and PAK1. It plays key roles in processes like cell migration, proliferation, and T-cell activation. NCK1 is highly expressed in various tissues and regulates growth factor receptor signaling, including pathways like MAPK/ERK and PI3K. Dysregulation of NCK1 is associated with cancer progression, metastasis, and immune system dysfunction. Knockout studies show defects in actin dynamics, impaired cell movement, and reduced T-cell activation, highlighting its importance in cytoskeletal signaling and cellular communication.
Productos relacionados
Cytoplasmic Protein NCK1 (NCK1) Antibody
NCK1 Antibody is a Rabbit Polyclonal antibody against NCK1. The protein encoded by this gene is one of the signaling and…
Ver producto
Cytoplasmic Protein NCK1 (NCK1) Antibody
The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 …
Ver producto
Cytoplasmic Protein NCK1 (NCK1) Antibody
The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 …
Ver producto