Human Cytoplasmic protein NCK1 (NCK1) ELISA Kit

Este producto es parte de NCK adaptor protein
Human Cytoplasmic protein NCK1 (NCK1) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for NCK1

proveedor

Abbexa

reference

abx534659

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Cytoplasmic protein NCK1 (NCK1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Cytoplasmic protein NCK1 (NCK1) concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

NCK1 is a cytoplasmic adaptor protein containing three SH3 domains and one SH2 domain, which allows it to mediate interactions between receptor tyrosine kinases (RTKs) and downstream effectors in signaling pathways. NCK1 is involved in actin cytoskeleton reorganization, cell motility, and immune synapse formation by linking signaling proteins such as WASP, WAVE, and PAK1. It plays key roles in processes like cell migration, proliferation, and T-cell activation. NCK1 is highly expressed in various tissues and regulates growth factor receptor signaling, including pathways like MAPK/ERK and PI3K. Dysregulation of NCK1 is associated with cancer progression, metastasis, and immune system dysfunction. Knockout studies show defects in actin dynamics, impaired cell movement, and reduced T-cell activation, highlighting its importance in cytoskeletal signaling and cellular communication.

Características del producto

category

ELISA Kits


immunogen target

Cytoplasmic protein NCK1 (NCK1)


reactivity

Human


test range

0.156 ng/ml - 10 ng/ml


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

NCK1, NCK, NCKalpha, nck-1, NCK adaptor protein 1


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

NCK1


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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