Human CFTR(Cystic Fibrosis Transmembrane Conductance Regulator) ELISA Kit
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name
Human CFTR(Cystic Fibrosis Transmembrane Conductance Regulator) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EH2805
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Reactivity | human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 0.156-10ng/ml |
| Size 1 | 96T |
| Sample Type | Serum,Plasma,Tissue homogenates,Other biological fluids |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 6 months |
| UniProt ID | P13569 |
| Alias | ATP-binding cassette sub-family C member 7,CF,MRP7,ABC35,ABCC7,CFTR/MRP,TNR-CFTR,dJ760C5.1,Cystic fibrosis transmembrane conductance regulator,Channel conductance-controlling ATPase |
| Background | Elisa Kits CFTR |
| Status | RUO |
CF Transmembrane Conductance Regulator (ABCC7), widely known as the cystic fibrosis transmembrane conductance regulator (CFTR), is a chloride channel essential for maintaining ion and water balance across epithelial cell membranes. Mutations in the CFTR gene cause cystic fibrosis (CF), a life-threatening genetic disorder that leads to thick mucus buildup in the lungs, pancreas, and other organs. As an ATP-gated channel, ABCC7 regulates chloride and bicarbonate secretion, influencing fluid viscosity and pH in various tissues. Beyond ion transport, CFTR modulates inflammation and immune responses, contributing to its broader physiological significance. Therapeutic interventions targeting CFTR, such as small-molecule modulators, have revolutionized CF management, improving lung function and quality of life for many patients. Additionally, CFTR dysfunction has been implicated in other conditions like chronic obstructive pulmonary disease (COPD) and pancreatitis, underlining its relevance in diverse respiratory and gastrointestinal diseases.
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