Human Caspase Recruitment Domain-Containing Protein 9 (CARD9) ELISA Kit
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Description
Human Caspase Recruitment Domain-Containing Protein 9 (CARD9) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Caspase Recruitment Domain Family, Member 9 (CARD9) concentrations in tissue homogenates, cell lysates and other biological fluids.
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Product specifications
| Category | ELISA Kits |
| Immunogen Target | Caspase Recruitment Domain-Containing Protein 9 (CARD9) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.313 ng/ml - 20 ng/ml |
| Sensitivity | < 0.19 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9H257 |
| Gene ID | 64170 |
| OMIM | 212050 |
| Alias | CARD9, CANDF2,Hcard9,IMD103 |
| Background | Elisa kits for CARD9 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
CARD9 is a key protein in the immune response, particularly in the signaling pathways of innate immunity. It is involved in activating the NF-κB signaling pathway, which plays a crucial role in inflammation and immune cell activation. CARD9 acts as an adaptor protein that connects pattern recognition receptors, such as C-type lectin receptors (CLRs), to downstream signaling pathways. This enables the recognition of microbial pathogens and triggers an immune response. Specifically, CARD9 is important in the recognition of fungal and bacterial infections, where it contributes to the activation of inflammatory cytokines and the recruitment of immune cells. Mutations or deficiencies in CARD9 can lead to immune system dysfunctions, including increased susceptibility to fungal infections and certain autoimmune diseases. CARD9 has therefore emerged as a critical target for understanding and potentially treating immune-related disorders and infections.
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