Human C-Type Lectin Domain Family 4 Member A (CLEC4A) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for CLEC4A
proveedor
Abbexareference
abx507125Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human C-type lectin domain family 4 member A (CLEC4A) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human C-type lectin domain family 4 member A (CLEC4A) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
CLEC4A (C-type lectin domain family 4 member A), also known as DCIR (dendritic cell immunoreceptor), is a receptor found on the surface of various immune cells, particularly dendritic cells (DCs) and monocytes. CLEC4A is part of the C-type lectin receptor (CLR) family, a group of proteins that play key roles in the immune system, especially in pathogen recognition, immune homeostasis, and inflammatory responses. As a member of this family, CLEC4A can recognize and bind to carbohydrate structures found on pathogens, self-antigens, and damaged cells. This binding facilitates immune responses and communication between cells of the immune system. CLEC4A has an important immunomodulatory role and is involved in both activating and inhibitory signaling pathways. Its ability to bind self-antigens and regulate immune responses is critical in maintaining immune tolerance, thus preventing autoimmune responses. Its expression in dendritic cells and other antigen-presenting cells highlights its relevance in adaptive immunity, where it influences T-cell activation and the shaping of immune responses. Additionally, CLEC4A is implicated in various autoimmune diseases and infections, making it an important target for therapeutic research.
Características del producto
category
ELISA Kits
immunogen target
C-Type Lectin Domain Family 4 Member A (CLEC4A)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.06 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
DCIR,LLIR,CD367,DDB27,hDCIR,CLECSF6,HDCGC13P,C-type lectin DDB27,C-type lectin superfamily member 6,Dendritic cell immunoreceptor,Lectin-like immunoreceptor
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
CLEC4A
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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