Human Tyrosine-Protein Kinase Mer (MERTK) Protein
234€ (10 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human Tyrosine-Protein Kinase Mer (MERTK) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx167063
tested applications
WB, SDS-PAGE
Description
Tyrosine-Protein Kinase Mer Protein is a recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Tyrosine-Protein Kinase Mer (MERTK) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 35.0 kDa Observed MW (SDS-PAGE): 32 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Leu587-Leu858 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q12866 |
| Gene ID | 10461 |
| NCBI Accession | NP_006334.2 |
| OMIM | 604705 |
| Alias | MER,RP38,c-Eyk,c-mer,Tyro12,Receptor tyrosine kinase MerTK,Proto-oncogene c-Mer |
| Background | Protein MERTK |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
MERTK (MER Proto-Oncogene, Tyrosine Kinase) is a member of the TAM (TYRO3, AXL, and MERTK) receptor tyrosine kinase family, which plays a crucial role in the regulation of immune response, cell survival, migration, and phagocytosis. This gene was identified due to its homology with the avian oncogene v-Mer and is involved in the clearance of apoptotic cells and immune tolerance. The MERTK protein is primarily expressed in macrophages, dendritic cells, and retinal pigment epithelial cells. Dysregulation of MERTK has been implicated in various diseases, including cancer, autoimmune disorders, and retinal degenerative diseases.
Related Products
Human Mer/MERTK(Tyrosine-protein kinase Mer) ELISA Kit
Ver Producto
Tyrosine-Protein Kinase Mer (MERTK) Antibody
MERTK Antibody is a Rabbit Polyclonal antibody against MERTK.
Ver Producto
Tyrosine-Protein Kinase Mer (MERTK) Antibody
Rabbit polyclonal antibody against MERTK protein. Immunogen region is N-terminal.
Ver Producto