Human Tyrosine-Protein Kinase Mer (MERTK) ELISA Kit

Este producto es parte de MERTK - MER proto-oncogene, tyrosine kinase
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643.5€ (96 tests)

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935106861
info@markelab.com
name
Human Tyrosine-Protein Kinase Mer (MERTK) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx152310
tested applications
ELISA

Description

Human Tyrosine-Protein Kinase Mer (MERTK) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Tyrosine-Protein Kinase Mer (MERTK) concentrations in tissue homogenates, cell lysates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Tyrosine-Protein Kinase Mer (MERTK)

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
ELISA Kits
Immunogen Target
Tyrosine-Protein Kinase Mer (MERTK)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.312 ng/ml - 20 ng/ml
Sensitivity
< 0.13 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q12866
Gene ID
10461
NCBI Accession
NP_006334.2
OMIM
604705
Alias
MER,RP38,c-Eyk,c-mer,Tyro12,Receptor tyrosine kinase MerTK,Proto-oncogene c-Mer
Background
Elisa kits for MERTK
Status
RUO
Note
Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

MERTK (MER Proto-Oncogene, Tyrosine Kinase) is a member of the TAM (TYRO3, AXL, and MERTK) receptor tyrosine kinase family, which plays a crucial role in the regulation of immune response, cell survival, migration, and phagocytosis. This gene was identified due to its homology with the avian oncogene v-Mer and is involved in the clearance of apoptotic cells and immune tolerance. The MERTK protein is primarily expressed in macrophages, dendritic cells, and retinal pigment epithelial cells. Dysregulation of MERTK has been implicated in various diseases, including cancer, autoimmune disorders, and retinal degenerative diseases.

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