Human BTB/POZ domain-containing protein KCTD16 (KCTD16) ELISA Kit
715€ (96 tests)
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name
Human BTB/POZ domain-containing protein KCTD16 (KCTD16) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx529518
tested applications
ELISA
Description
Human BTB/POZ domain-containing protein KCTD16 (KCTD16) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human BTB/POZ domain-containing protein KCTD16 (KCTD16) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | BTB/POZ domain-containing protein KCTD16 (KCTD16) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q68DU8 |
| OMIM | 613423 |
| Alias | KCTD16 |
| Background | Elisa kits for KCTD16 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
KCTD16 is another member of the KCTD family that functions as an auxiliary subunit of GABA-B receptors, modulating their pharmacological and signaling properties. KCTD16 specifically regulates the kinetics of GABA-B receptor activation and desensitization, influencing inhibitory neurotransmission in the central nervous system. It is widely expressed in brain regions associated with cognition, motor activity, and emotional regulation, playing a role in synaptic plasticity and neuronal excitability. KCTD16 interacts with GABA-B receptor subunits to enhance receptor sensitivity and prolong inhibitory signaling, which is critical for maintaining neural network stability. Dysregulation of KCTD16 has been linked to psychiatric disorders, including schizophrenia, anxiety, and depression, where impaired GABA-B receptor function contributes to disrupted inhibitory signaling. Beyond the nervous system, KCTD16 may participate in protein degradation pathways through its BTB/POZ domain, influencing cellular homeostasis. Its ability to fine-tune GABA-B receptor signaling positions KCTD16 as a key target for therapeutic interventions aimed at restoring inhibitory balance in neurological and psychiatric disorders.
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