Human Brother of CDO (BOC) ELISA Kit
715€ (96 tests)
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935106861
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name
Human Brother of CDO (BOC) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx503904
tested applications
ELISA
Description
Human Brother of CDO (BOC) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Brother of CDO (BOC) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Brother of CDO (BOC) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9BWV1 |
| Alias | Boi,CDON2,Brother of CDO,Protein BOC |
| Background | Elisa kits for BOC |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
BOC is a member of the immunoglobulin (Ig) superfamily and functions as a cell surface receptor involved in cell adhesion, axon guidance, and myogenic differentiation. It is predominantly expressed in neural and muscle tissues, where it interacts with other cell adhesion molecules and receptors to facilitate cell-cell communication and signaling. BOC plays a crucial role in the Hedgehog (Hh) signaling pathway by acting as a co-receptor for Sonic Hedgehog (Shh), enhancing its signaling and influencing developmental processes such as neural tube patterning and limb formation. Dysregulation of BOC has been linked to aberrant cell proliferation and migration, implicating its role in cancer progression and metastasis. Structurally, BOC contains multiple Ig-like domains and fibronectin type III repeats, which mediate its interactions with extracellular ligands and intracellular signaling molecules. Studies have shown that BOC modulates the balance between cell proliferation and differentiation, particularly in myogenic and neuronal contexts. It is also implicated in synaptic development and plasticity, supporting its diverse functional roles. Emerging research highlights its potential as a therapeutic target in cancers where Hedgehog signaling is dysregulated, such as basal cell carcinoma and medulloblastoma.
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