Human Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (ARFGEF3) ELISA Kit
715€ (96 tests)
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name
Human Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (ARFGEF3) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx503782
tested applications
ELISA
Description
Human Brefeldin A-Inhibited Guanine Nucleotide-Exchange Protein 3 (ARFGEF3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Brefeldin A-Inhibited Guanine Nucleotide-Exchange Protein 3 (ARFGEF3) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (ARFGEF3) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q5TH69 |
| OMIM | 617411 |
| Alias | BIG3,A7322,C6orf92,PPP1R33,KIAA1244,Brefeldin A-inhibited guanine nucleotide-exchange protein 3 |
| Background | Elisa kits for ARFGEF3 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ARFGEF family member 3 (ARFGEF3) is another guanine nucleotide exchange factor that activates ARF proteins, playing a crucial role in regulating intracellular trafficking and actin cytoskeleton organization ARFGEF3 works by catalyzing the exchange of GDP for GTP on ARF proteins, enabling ARF-mediated signaling and regulating processes like vesicular trafficking, membrane dynamics, and cell signaling It is involved in cellular events such as endocytosis, exocytosis, and the formation of membrane-bound organelles ARFGEF3 also influences actin dynamics, which are essential for cell movement, adhesion, and shape maintenance Additionally, ARFGEF3 has been linked to processes in the immune system, particularly in the regulation of immune cell activation and trafficking Disruption in ARFGEF3 activity has been associated with various diseases, including cancer, where altered cell trafficking and actin dynamics contribute to metastasis and tumor progression It also plays a role in other conditions such as neurodegenerative diseases, where disruptions in cellular trafficking and signaling may contribute to cellular dysfunction
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