Human Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (ARFGEF3) ELISA Kit

Name: Human Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (ARFGEF3) ELISA Kit
Brand: Abbexa
SKU: abx503782
Price: 715 EUR
Availability: OnlineOnly

Este producto es parte de ARFGEF - ADP ribosylation factor guanine nucleotide exchange factor

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for ARFGEF3

proveedor

Abbexa

reference

abx503782

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Brefeldin A-Inhibited Guanine Nucleotide-Exchange Protein 3 (ARFGEF3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Brefeldin A-Inhibited Guanine Nucleotide-Exchange Protein 3 (ARFGEF3) concentrations in tissue homogenates, cell lysates and other biological fluids.

Background

ARFGEF family member 3 (ARFGEF3) is another guanine nucleotide exchange factor that activates ARF proteins, playing a crucial role in regulating intracellular trafficking and actin cytoskeleton organization ARFGEF3 works by catalyzing the exchange of GDP for GTP on ARF proteins, enabling ARF-mediated signaling and regulating processes like vesicular trafficking, membrane dynamics, and cell signaling It is involved in cellular events such as endocytosis, exocytosis, and the formation of membrane-bound organelles ARFGEF3 also influences actin dynamics, which are essential for cell movement, adhesion, and shape maintenance Additionally, ARFGEF3 has been linked to processes in the immune system, particularly in the regulation of immune cell activation and trafficking Disruption in ARFGEF3 activity has been associated with various diseases, including cancer, where altered cell trafficking and actin dynamics contribute to metastasis and tumor progression It also plays a role in other conditions such as neurodegenerative diseases, where disruptions in cellular trafficking and signaling may contribute to cellular dysfunction

Características del producto

immunogen target

Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (ARFGEF3)

reactivity

Human

test range

0.156 ng/ml - 10 ng/ml

assay data

Quantitative

form

Lyophilized

detection method

Colorimetric

sample type

Tissue homogenates, cell lysates and other biological fluids.

size 1

96 tests

alias

BIG3,A7322,C6orf92,PPP1R33,KIAA1244,Brefeldin A-inhibited guanine nucleotide-exchange protein 3

storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.

or code

ARFGEF3

dry ice

uniprot id

https://www.uniprot.org/uniprotkb/Q5TH69

note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

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