Human Brain Specific Angiogenesis Inhibitor 3 / BAI3 (ADGRB3) Protein

Este producto es parte de ADGRB - Adhesion G protein-coupled receptor B
Human Brain Specific Angiogenesis Inhibitor 3 / BAI3 (ADGRB3) Protein

Pida mas información

935106861

info@markelab.com

Precio

221€ (10 µg)

Protein ADGRB3

proveedor

Abbexa

reference

abx650653

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Human Brain Specific Angiogenesis Inhibitor 3 / BAI3 (ADGRB3) Protein is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).


Background

ADGRB3, known as BAI3, is a GPCR highly expressed in the brain, where it regulates synaptic development and neuronal connectivity. It plays a role in dendritic arborization and synapse formation, supporting neuronal circuitry and communication. ADGRB3 interacts with proteins involved in synaptic organization and phagocytosis, contributing to the removal of apoptotic neurons and cellular debris. Dysregulation of ADGRB3 has been associated with autism spectrum disorders and other neurodevelopmental conditions due to its role in synaptic refinement. Additionally, it is implicated in vascular homeostasis, although its angiogenic functions are less defined compared to ADGRB1. ADGRB3’s dual involvement in synaptic and vascular processes highlights its importance in neurovascular coupling and overall brain health.

Características del producto

category

Proteins and Peptides


origin

Human


host

E. coli


immunogen target

Brain Specific Angiogenesis Inhibitor 3 / BAI3 (ADGRB3)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 57.9 kDa Observed MW (SDS-PAGE): 58 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Cys30-Pro508 Tag: N-terminal His tag


expression

Recombinant


purity

> 90%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

ADGRB3


dry ice

No


availability

Shipped within 5-7 working days.


alias

ADGRB3,BAI3


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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reactivity

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