Brain Specific Angiogenesis Inhibitor 3 / BAI3 (ADGRB3) Antibody

Este producto es parte de ADGRB - Adhesion G protein-coupled receptor B
Product Graph
312€ (50 µl)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Brain Specific Angiogenesis Inhibitor 3 / BAI3 (ADGRB3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx148536
tested applications
WB

Description

Brain Specific Angiogenesis Inhibitor 3 / BAI3 (ADGRB3) Antibody is a Rabbit Polyclonal against ADGRB3.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Brain Specific Angiogenesis Inhibitor 3 / BAI3 (ADGRB3)
Host
Rabbit
Reactivity
Human, Mouse
Recommended Dilution
WB: 1/1000 - 1/3000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Purification
Purified by affinity chromatography using epitope-specific peptide.
Size 1
50 µl
Size 2
100 µl
Form
Liquid
Tested Applications
WB
Buffer
PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
O60242
Gene ID
577
Alias
ADGRB3,BAI3
Background
Antibody anti-ADGRB3
Status
RUO
Note
Concentration: 1 mg/ml - 

Descripción

ADGRB3, known as BAI3, is a GPCR highly expressed in the brain, where it regulates synaptic development and neuronal connectivity. It plays a role in dendritic arborization and synapse formation, supporting neuronal circuitry and communication. ADGRB3 interacts with proteins involved in synaptic organization and phagocytosis, contributing to the removal of apoptotic neurons and cellular debris. Dysregulation of ADGRB3 has been associated with autism spectrum disorders and other neurodevelopmental conditions due to its role in synaptic refinement. Additionally, it is implicated in vascular homeostasis, although its angiogenic functions are less defined compared to ADGRB1. ADGRB3’s dual involvement in synaptic and vascular processes highlights its importance in neurovascular coupling and overall brain health.

Related Products

EH1335

Human BAI3 (Brain-specific angiogenesis inhibitor 3) ELISA Kit

Ver Producto
FNab00792

ADGRB3-Specific antibody

Ver Producto
Pr22314

Recombinant Human BAI3

Ver Producto