Human Brain Specific Angiogenesis Inhibitor 1 / BAI1 (ADGRB1) Protein
208€ (10 µg)
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935106861
info@markelab.com
name
Human Brain Specific Angiogenesis Inhibitor 1 / BAI1 (ADGRB1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx652708
tested applications
WB, SDS-PAGE
Description
Human Brain Specific Angiogenesis Inhibitor 1 / BAI1 (ADGRB1) Protein is a Recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Brain Specific Angiogenesis Inhibitor 1 / BAI1 (ADGRB1) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 64.1 kDa Observed MW (SDS-PAGE): 64 kDa Concentration: Prior to lyophilization: 50 µg/ml Sequence Fragment: Ala31-Pro350 Tag: N-terminal His tag and GST tag |
| Expression | Recombinant |
| Purity | > 80% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized Reconstitute in ddH2O to a concentration 0.1-0.2 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 5% Trehalose. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | ADGRB1,BAI1,GDAIF |
| Background | Protein ADGRB1 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
ADGRB1, also known as BAI1 (Brain-Specific Angiogenesis Inhibitor 1), is a member of the adhesion G protein-coupled receptor (GPCR) family predominantly expressed in the brain. It plays a critical role in inhibiting angiogenesis, promoting synaptic plasticity, and mediating phagocytic clearance of apoptotic cells and pathogens. Structurally, ADGRB1 contains multiple extracellular domains that facilitate interactions with matrix proteins and apoptotic cell markers. Dysregulation of ADGRB1 is associated with glioblastoma, as it suppresses tumor angiogenesis and growth, and its loss can contribute to tumor progression. Additionally, it has been implicated in synaptic function and neuronal health, with potential roles in neurodevelopmental disorders and neurodegeneration. ADGRB1’s ability to link extracellular signals to intracellular pathways highlights its importance in vascular regulation and brain function.
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