935106861
info@markelab.com
Precio
225€ (5 µg)
Human Tumor Necrosis Factor Ligand Superfamily Member 13B / BAFF (TNFSF13B) Protein is a recombinant human cytokine expressed in E. coli, containing a His tag.
TNFSF13B, commonly known as BAFF (B-cell activating factor), is a cytokine that belongs to the tumor necrosis factor (TNF) superfamily and is critical for B cell survival, maturation, and immune function. This ligand is primarily produced by myeloid cells, such as monocytes, macrophages, and dendritic cells, but can also be secreted by activated T cells. BAFF plays a pivotal role in maintaining peripheral B cell populations, supporting antibody production, and promoting immune tolerance. It interacts with specific receptors on B cells and related immune cells, including BAFF-R, TACI (Transmembrane Activator and Calcium-Modulating Cyclophilin Ligand Interactor), and BCMA (B Cell Maturation Antigen), to initiate intracellular signaling pathways crucial for B cell homeostasis and function. Dysregulation of BAFF expression or receptor binding is associated with autoimmune diseases, such as systemic lupus erythematosus (SLE), multiple sclerosis, and rheumatoid arthritis.
Proteins and Peptides
Human
E. coli
Tumor Necrosis Factor Ligand Superfamily Member 13B / BAFF (TNFSF13B)
E. coli
Unconjugated
Liquid
SDS-PAGE
5 µg
20 µg
1 mg
Recombinant
> 95% (SDS-PAGE)
Purified by proprietary chromatographic techniques. 0.2 µm filtered prior to lyophilization.
PBS, pH 7.4, containing 10% glycerol.
For short-term storage, store at 4 °C for up to 4 weeks. For long-term storage, aliquot and store at -20 °C. For long-term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles.
TNFSF13B
No
Shipped within 5-10 working days.
Tumor necrosis factor ligand superfamily member 13B,DTL,BAFF,BLYS,CD257,TALL1,THANK,ZTNF4,TALL-1,TNLG7A,TNFSF20,B lymphocyte stimulator,BLyS,Dendritic cell-derived TNF-like molecule,TNF- and APOL-related leukocyte expressed ligand 1
This product is for research use only. <p></p> Not for human consumption, cosmetic, therapeutic or diagnostic use.
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