935106861
info@markelab.com
Precio
618.75€ (96 tests)
Human Tumor Necrosis Factor Ligand Superfamily Member 13B (BAFF/CD257) Chemiluminescent Immunoassay (CLIA) Kit is a Chemiluminescent Immunoassay (CLIA) kit against Tumor Necrosis Factor Ligand Superfamily Member 13B (BAFF/CD257).
Human B-Cell Activating Factor (BAFF/CD257) CLIA Kit es un kit CLIA contra el B-Cell Activating Factor (BAFF/CD257) en humanos.
TNFSF13B, commonly known as BAFF (B-cell activating factor), is a cytokine that belongs to the tumor necrosis factor (TNF) superfamily and is critical for B cell survival, maturation, and immune function. This ligand is primarily produced by myeloid cells, such as monocytes, macrophages, and dendritic cells, but can also be secreted by activated T cells. BAFF plays a pivotal role in maintaining peripheral B cell populations, supporting antibody production, and promoting immune tolerance. It interacts with specific receptors on B cells and related immune cells, including BAFF-R, TACI (Transmembrane Activator and Calcium-Modulating Cyclophilin Ligand Interactor), and BCMA (B Cell Maturation Antigen), to initiate intracellular signaling pathways crucial for B cell homeostasis and function. Dysregulation of BAFF expression or receptor binding is associated with autoimmune diseases, such as systemic lupus erythematosus (SLE), multiple sclerosis, and rheumatoid arthritis.
CLIA Kits
Tumor Necrosis Factor Ligand Superfamily Member 13B / BAFF (TNFSF13B)
Human
15.6 pg/ml - 1000 pg/ml
9.38 pg/ml
Sandwich
Quantitative
Chemiluminescent
Serum, plasma and other biological fluids.
96 tests
Tumor necrosis factor ligand superfamily member 13B,DTL,BAFF,BLYS,CD257,TALL1,THANK,ZTNF4,TALL-1,TNLG7A,TNFSF20,B lymphocyte stimulator,BLyS,Dendritic cell-derived TNF-like molecule,TNF- and APOL-related leukocyte expressed ligand 1
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
TNFSF13B
No
El rango y la sensibilidad pueden variar. Le recomendamos contactar con nosotros a fin de obtener la última información sobre posibles actualizaciones, que no estén representadas en este catalogo. Si necesita un rango específico, contáctenos y trataremos de ayudarle. Consulte sobre posible información que pueda ayudarle a elegir la dilución apropiada para sus muestras. Los kits CLIA están optimizados para la detección de muestras nativas, las proteínas recombinantes, pueden resultar problemáticas a causa de diferencias en la secuencia o cambios en la estructura terciaria.
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