935106861
info@markelab.com
Precio
812.5€ (96 tests)
Human ATP Binding Cassette Transporter C3 (ABCC3) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Tissue homogenates, cell lysates and other biological fluids.
Human ATP Binding Cassette Transporter C3 (ABCC3) CLIA Kit es un kit CLIA tipo Sandwich para su uso con homogeneizados de tejido, lisados de células y otros fluidos biológicos.
ABCC3, also known as multidrug resistance-associated protein 3 (MRP3), is expressed on the basolateral membrane of hepatocytes, enterocytes, and other epithelial cells. It facilitates the efflux of organic anions, including bile acids, glucuronides, and sulfated metabolites, from cells into the bloodstream for subsequent excretion via the kidneys. ABCC3 is upregulated in conditions where bile flow is impaired, such as cholestasis, serving as a compensatory mechanism to reduce intracellular bile acid toxicity. It also transports drug conjugates and metabolites, playing a critical role in drug resistance and disposition. ABCC3 is highly expressed in tissues such as the liver, intestines, and pancreas, where it contributes to detoxification and cellular protection. Dysregulation of ABCC3 has been linked to altered drug pharmacokinetics and resistance to chemotherapy.
CLIA Kits
ATP Binding Cassette Transporter C3 (ABCC3)
Human
0.312 ng/ml - 20 ng/ml
< 0.113 ng/ml
Sandwich
Quantitative
Lyophilized
Chemiluminescent
Tissue homogenates, cell lysates and other biological fluids.
96 tests
5 × 96 tests
10 × 96 tests
ABC31,EST90757,MLP2,Multidrug resistance-associated protein 3
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
ABCC3
No
El rango y la sensibilidad pueden variar. Le recomendamos contactar con nosotros a fin de obtener la última información sobre posibles actualizaciones, que no estén representadas en este catalogo. Si necesita un rango específico, contáctenos y trataremos de ayudarle. Consulte sobre posible información que pueda ayudarle a elegir la dilución apropiada para sus muestras. Los kits CLIA están optimizados para la detección de muestras nativas, las proteínas recombinantes, pueden resultar problemáticas a causa de diferencias en la secuencia o cambios en la estructura terciaria.
Precio a consultar
Ver másRabbit polyclonal antibody against ABCC3 protein. Immunogen region is Internal.
43.75€ (10 µg)
Ver másThe protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins...
281.25€ (80 µl)
Ver más