Human ATP Binding Cassette Transporter C10 (ABCC10) Protein
234€ (10 µg)
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935106861
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name
Human ATP Binding Cassette Transporter C10 (ABCC10) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx167105
tested applications
WB, SDS-PAGE
Description
ATP Binding Cassette Transporter C10 Protein is a recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | ATP Binding Cassette Transporter C10 (ABCC10) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 30.4 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Val1246-Pro1492 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q5T3U5 |
| Alias | EST182763,MRP7,SIMRP7 |
| Background | Protein ABCC10 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
ATP-binding cassette subfamily C member 10 (ABCC10), also known as multidrug resistance-associated protein 7 (MRP7), is part of the ABC transporter family involved in ATP-dependent efflux of endogenous and exogenous compounds across cellular membranes. ABCC10 plays a role in multidrug resistance by transporting chemotherapeutic agents such as taxanes and nucleoside analogs. It is widely expressed in various tissues, including the liver, lungs, and intestines, contributing to detoxification and xenobiotic metabolism. The protein contains two transmembrane domains and two nucleotide-binding domains, characteristic of ABC transporters. Dysregulation or overexpression of ABCC10 is associated with cancer drug resistance and altered pharmacokinetics of therapeutic agents.
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