Human ATP Binding Cassette Transporter C10 (ABCC10) CLIA Kit

Este producto es parte de ABCC - ATP binding cassette subfamily C
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845€ (96 tests)

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935106861
info@markelab.com
name
Human ATP Binding Cassette Transporter C10 (ABCC10) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx496170
tested applications
CLIA

Description

Human ATP Binding Cassette Transporter C10 (ABCC10) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryCLIA Kits
Immunogen TargetATP Binding Cassette Transporter C10 (ABCC10)
ReactivityHuman
Detection MethodChemiluminescent
Assay DataQuantitative
Assay TypeSandwich
Test Range0.156 ng/ml - 10 ng/ml
Sensitivity< 0.061 ng/ml
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Size 196 tests
Size 25 × 96 tests
Size 310 × 96 tests
FormLyophilized
Tested ApplicationsCLIA
Sample TypeTissue homogenates, cell lysates and other biological fluids.
AvailabilityShipped within 5-20 working days.
Storage Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry IceNo
AliasEST182763,MRP7,SIMRP7
BackgroundCLIA Kits ABCC10
StatusRUO
NoteThe validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

ATP-binding cassette subfamily C member 10 (ABCC10), also known as multidrug resistance-associated protein 7 (MRP7), is part of the ABC transporter family involved in ATP-dependent efflux of endogenous and exogenous compounds across cellular membranes. ABCC10 plays a role in multidrug resistance by transporting chemotherapeutic agents such as taxanes and nucleoside analogs. It is widely expressed in various tissues, including the liver, lungs, and intestines, contributing to detoxification and xenobiotic metabolism. The protein contains two transmembrane domains and two nucleotide-binding domains, characteristic of ABC transporters. Dysregulation or overexpression of ABCC10 is associated with cancer drug resistance and altered pharmacokinetics of therapeutic agents.

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