Human ATP Binding Cassette Transporter C10 (ABCC10) CLIA Kit

Este producto es parte de ABCC - ATP binding cassette subfamily C
Human ATP Binding Cassette Transporter C10 (ABCC10) CLIA Kit

Pida mas información

935106861

info@markelab.com

Precio

812.5€ (96 tests)

CLIA Kits ABCC10

proveedor

Abbexa

reference

abx496170

Tested Applications

CLIA

reactivity

Human

status

RUO

clonality

Descripción

Human ATP Binding Cassette Transporter C10 (ABCC10) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Tissue homogenates, cell lysates and other biological fluids.


Human ATP Binding Cassette Transporter C10 (ABCC10) CLIA Kit es un kit CLIA tipo Sandwich para su uso con homogeneizados de tejido, lisados celulares y otros fluidos biológicos.


Background

ATP-binding cassette subfamily C member 10 (ABCC10), also known as multidrug resistance-associated protein 7 (MRP7), is part of the ABC transporter family involved in ATP-dependent efflux of endogenous and exogenous compounds across cellular membranes. ABCC10 plays a role in multidrug resistance by transporting chemotherapeutic agents such as taxanes and nucleoside analogs. It is widely expressed in various tissues, including the liver, lungs, and intestines, contributing to detoxification and xenobiotic metabolism. The protein contains two transmembrane domains and two nucleotide-binding domains, characteristic of ABC transporters. Dysregulation or overexpression of ABCC10 is associated with cancer drug resistance and altered pharmacokinetics of therapeutic agents.

Características del producto

category

CLIA Kits


immunogen target

ATP Binding Cassette Transporter C10 (ABCC10)


reactivity

Human


test range

0.156 ng/ml - 10 ng/ml


sensitivity

< 0.061 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Chemiluminescent


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

EST182763,MRP7,SIMRP7


storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit


or code

ABCC10


dry ice

No


note

El rango y la sensibilidad pueden variar. Le recomendamos contactar con nosotros a fin de obtener la última información sobre posibles actualizaciones, que no estén representadas en este catalogo. Si necesita un rango específico, contáctenos y trataremos de ayudarle. Consulte sobre posible información que pueda ayudarle a elegir la dilución apropiada para sus muestras. Los kits CLIA están optimizados para la detección de muestras nativas, las proteínas recombinantes, pueden resultar problemáticas a causa de diferencias en la secuencia o cambios en la estructura terciaria.


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