Human ATP Binding Cassette Transporter C10 (ABCC10) CLIA Kit
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935106861
info@markelab.com
Precio
812.5€ (96 tests)
CLIA Kits ABCC10
proveedor
Abbexareference
abx496170Tested Applications
CLIAreactivity
Humanstatus
RUOclonality
Descripción
Human ATP Binding Cassette Transporter C10 (ABCC10) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Tissue homogenates, cell lysates and other biological fluids.
Human ATP Binding Cassette Transporter C10 (ABCC10) CLIA Kit es un kit CLIA tipo Sandwich para su uso con homogeneizados de tejido, lisados celulares y otros fluidos biológicos.
Background
ATP-binding cassette subfamily C member 10 (ABCC10), also known as multidrug resistance-associated protein 7 (MRP7), is part of the ABC transporter family involved in ATP-dependent efflux of endogenous and exogenous compounds across cellular membranes. ABCC10 plays a role in multidrug resistance by transporting chemotherapeutic agents such as taxanes and nucleoside analogs. It is widely expressed in various tissues, including the liver, lungs, and intestines, contributing to detoxification and xenobiotic metabolism. The protein contains two transmembrane domains and two nucleotide-binding domains, characteristic of ABC transporters. Dysregulation or overexpression of ABCC10 is associated with cancer drug resistance and altered pharmacokinetics of therapeutic agents.
Características del producto
category
CLIA Kits
immunogen target
ATP Binding Cassette Transporter C10 (ABCC10)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.061 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Chemiluminescent
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
EST182763,MRP7,SIMRP7
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
ABCC10
dry ice
No
note
El rango y la sensibilidad pueden variar. Le recomendamos contactar con nosotros a fin de obtener la última información sobre posibles actualizaciones, que no estén representadas en este catalogo. Si necesita un rango específico, contáctenos y trataremos de ayudarle. Consulte sobre posible información que pueda ayudarle a elegir la dilución apropiada para sus muestras. Los kits CLIA están optimizados para la detección de muestras nativas, las proteínas recombinantes, pueden resultar problemáticas a causa de diferencias en la secuencia o cambios en la estructura terciaria.
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