Human ATP Binding Cassette Subfamily F Member 1 (ABCF1) ELISA Kit
715€ (96 tests)
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name
Human ATP Binding Cassette Subfamily F Member 1 (ABCF1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx385547
tested applications
ELISA
Description
Human ATP Binding Cassette Subfamily F Member 1 (ABCF1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human ATP Binding Cassette Transporter F1 (ABCF1) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | ATP Binding Cassette Subfamily F Member 1 (ABCF1) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.313 ng/ml - 20 ng/ml |
| Sensitivity | < 0.19 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q8NE71 |
| Gene ID | 23 |
| OMIM | 603429 |
| Alias | ABC27,ABC50 |
| Background | Elisa kits for ABCF1 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ABCF1 is an ATP-binding cassette (ABC) protein that lacks transmembrane domains, distinguishing it from traditional ABC transporters involved in substrate transport. Instead, ABCF1 functions primarily in regulating translation initiation and immune responses. It facilitates the assembly of the translation machinery by interacting with ribosomal subunits, ensuring efficient protein synthesis. ABCF1 is ubiquitously expressed but is particularly abundant in immune cells, where it plays a role in regulating the production of inflammatory cytokines, such as tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6). Its involvement in inflammatory signaling pathways has implicated it in autoimmune diseases, including rheumatoid arthritis, where dysregulation of ABCF1 contributes to chronic inflammation. Additionally, ABCF1 is associated with cancer progression due to its role in sustaining protein homeostasis and immune signaling in the tumor microenvironment. Dysregulation of ABCF1 can disrupt translational control and immune balance, highlighting its significance in both cellular function and disease pathogenesis.
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