Human ATP-Binding Cassette Subfamily B Member 5 (ABCB5) ELISA Kit
643.5€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human ATP-Binding Cassette Subfamily B Member 5 (ABCB5) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx156772
tested applications
ELISA
Description
Human ATP-Binding Cassette Subfamily B Member 5 (ABCB5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human ATP-Binding Cassette Subfamily B Member 5 (ABCB5) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | ATP-Binding Cassette Subfamily B Member 5 (ABCB5) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.06 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Gene ID | 340273 |
| NCBI Accession | NM_178559.5 |
| OMIM | 611785 |
| Alias | ABCB5alphabeta,EST422562 |
| Background | Elisa kits for ABCB5 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ABCB5 is a transmembrane ATP-binding cassette (ABC) transporter known for its roles in drug resistance, stem cell biology, and tissue repair. It is expressed in a variety of tissues, including melanocytes, the corneal epithelium, and cancer stem cells, particularly in melanoma. ABCB5 functions as a drug efflux pump, actively exporting chemotherapeutic agents out of cells, contributing to multidrug resistance in cancer. It is also a recognized marker of cancer stem cells, promoting tumor growth, metastasis, and resistance to standard therapies. Beyond its role in cancer, ABCB5 has been implicated in wound healing and tissue regeneration due to its expression in progenitor cells in damaged tissues. Structurally, ABCB5 contains transmembrane domains and ATP-binding sites that drive substrate transport through ATP hydrolysis. Dysregulation of ABCB5 is associated with cancer progression, chemoresistance, and impaired tissue repair, making it a promising therapeutic target in oncology and regenerative medicine.
Related Products
Human ABCB5 (ATP-binding cassette sub-family B member 5) ELISA Kit
Ver Producto
ABCB5 antibody
Ver Producto