Human ArfGAP With FG Repeats 2 (AGFG2) ELISA Kit

Este producto es parte de AGFG - Arf-GAP domain and FG repeat-containing protein
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715€ (96 tests)

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935106861
info@markelab.com
name
Human ArfGAP With FG Repeats 2 (AGFG2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx385659
tested applications
ELISA

Description

Human ArfGAP With FG Repeats 2 (AGFG2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human AGFG2 concentrations in serum, plasma and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
ELISA Kits
Immunogen Target
ArfGAP With FG Repeats 2 (AGFG2)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.313 ng/ml - 20 ng/ml
Sensitivity
< 0.188 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Serum, plasma and other biological fluids.
Availability
Shipped within 5-12 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
O95081
Gene ID
3268
OMIM
604019
Alias
HRBL,RABR
Background
Elisa kits for AGFG2
Status
RUO
Note
Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

AGFG2 is structurally similar to AGFG1, containing both an Arf-GAP domain and FG repeats, which enable its role in vesicular trafficking and RNA transport. AGFG2 is particularly important in the context of nuclear export of RNA and is implicated in regulating the intracellular movement of proteins and nucleic acids. It is expressed across a range of tissues but is most prominent in immune cells and the nervous system, where it participates in mRNA processing and cellular signaling. Like AGFG1, AGFG2 is also exploited by certain viruses, including HIV, to facilitate the export of viral RNA, highlighting its role in host-pathogen interactions. Dysregulation of AGFG2 may contribute to defects in RNA processing and trafficking, with potential implications in immune-related diseases and viral infections. Further studies are needed to fully understand its broader physiological and pathological roles.

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