AGFG2 antibody
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935106861
info@markelab.com
name
AGFG2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00211
tested applications
ELISA, WB, IHC, IF
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ArfGAP with FG repeats 2 (AGFG2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:200-1:2000; IF: 1:10-1:100; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 49 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | O95081 |
| Gene ID | 3268 |
| Alias | HRBL,RABR |
| Background | Antibody anti-AGFG2 |
| Status | RUO |
| Note | Mol. Weight 49 kDa |
AGFG2 is structurally similar to AGFG1, containing both an Arf-GAP domain and FG repeats, which enable its role in vesicular trafficking and RNA transport. AGFG2 is particularly important in the context of nuclear export of RNA and is implicated in regulating the intracellular movement of proteins and nucleic acids. It is expressed across a range of tissues but is most prominent in immune cells and the nervous system, where it participates in mRNA processing and cellular signaling. Like AGFG1, AGFG2 is also exploited by certain viruses, including HIV, to facilitate the export of viral RNA, highlighting its role in host-pathogen interactions. Dysregulation of AGFG2 may contribute to defects in RNA processing and trafficking, with potential implications in immune-related diseases and viral infections. Further studies are needed to fully understand its broader physiological and pathological roles.
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