ArfGAP With FG Repeats 2 (AGFG2) Antibody
364€ (100 µg)
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935106861
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name
ArfGAP With FG Repeats 2 (AGFG2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx230211
tested applications
ELISA, WB, IHC, IF/ICC
Description
AGFG2 Antibody is a Rabbit Polyclonal against AGFG2.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ArfGAP With FG Repeats 2 (AGFG2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/200 - 1/2000, IHC: 1/20 - 1/200, IF/ICC: 1/10 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O95081 |
| Gene ID | 3268 |
| OMIM | 604019 |
| Alias | HRBL,RABR |
| Background | Antibody anti-AGFG2 |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
AGFG2 is structurally similar to AGFG1, containing both an Arf-GAP domain and FG repeats, which enable its role in vesicular trafficking and RNA transport. AGFG2 is particularly important in the context of nuclear export of RNA and is implicated in regulating the intracellular movement of proteins and nucleic acids. It is expressed across a range of tissues but is most prominent in immune cells and the nervous system, where it participates in mRNA processing and cellular signaling. Like AGFG1, AGFG2 is also exploited by certain viruses, including HIV, to facilitate the export of viral RNA, highlighting its role in host-pathogen interactions. Dysregulation of AGFG2 may contribute to defects in RNA processing and trafficking, with potential implications in immune-related diseases and viral infections. Further studies are needed to fully understand its broader physiological and pathological roles.
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