Human ArfGAP With FG Repeats 1 (AGFG1) ELISA Kit
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Description
Human ArfGAP With FG Repeats 1 (AGFG1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human AGFG1 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | ArfGAP With FG Repeats 1 (AGFG1) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.094 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P52594 |
| Gene ID | 3267 |
| OMIM | 600862 |
| Alias | HRB,RAB,RIP |
| Background | Elisa kits for AGFG1 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
AGFG1 is a cytoplasmic protein that plays a key role in intracellular trafficking and RNA transport. It contains an Arf-GAP domain, which facilitates the regulation of small GTPases involved in vesicle formation, and FG repeats, which mediate interactions with nuclear pore complexes and RNA-binding proteins. AGFG1 is highly expressed in tissues such as the brain, immune cells, and reproductive tissues, where it participates in mRNA transport and localization. It is also involved in the HIV life cycle, specifically in the nuclear export of viral RNA, making it a potential therapeutic target for antiviral strategies. Dysregulation of AGFG1 has been associated with disruptions in intracellular transport and immune signaling, with emerging evidence suggesting its involvement in diseases such as viral infections and possibly cancer.
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