Human Arf-GAP With GTPase, ANK Repeat And PH Domain Containing Protein 2 (AGAP2) ELISA Kit

Este producto es parte de AGAP - Arf-GAP with GTPase ANK repeat and PH domain-containing protein
Human Arf-GAP With GTPase, ANK Repeat And PH Domain Containing Protein 2 (AGAP2) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for AGAP2

proveedor

Abbexa

reference

abx385656

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Arf-GAP With GTPase, ANK Repeat And PH Domain Containing Protein 2 (AGAP2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human AGAP2 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

AGAP2, also known as PIKE-A, plays a key role in regulating cell survival, growth signaling pathways, and intracellular transport. It interacts with phosphoinositide 3-kinase (PI3K), enhancing PI3K-Akt signaling and promoting anti-apoptotic responses. AGAP2 contains a GTPase domain, ankyrin repeats, and a PH domain, enabling its participation in vesicle trafficking, cytoskeletal dynamics, and endosomal transport. It is expressed in neurons, where it supports synaptic stability and neuronal survival, and is overexpressed in cancers such as glioblastomas, driving tumor growth and resistance to apoptosis. AGAP2’s dual roles in neuronal plasticity and oncogenesis make it a significant target for therapeutic research.

Características del producto

category

ELISA Kits


immunogen target

Arf-GAP With GTPase, ANK Repeat And PH Domain Containing Protein 2 (AGAP2)


reactivity

Human


test range

0.156 ng/ml - 10 ng/ml


sensitivity

< 0.094 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

CENTG1,GGAP2,PIKE


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

AGAP2


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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