Arf-GAP With GTPase, ANK Repeat And PH Domain Containing Protein 2 (AGAP2) Antibody
637€ (100 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Arf-GAP With GTPase, ANK Repeat And PH Domain Containing Protein 2 (AGAP2) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx111050
Tested Applications
ELISA, WB, IHC, IF/ICC
Description
Arfgap With Gtpase Domain, Ankyrin Repeat And Ph Domain 2 Antibody is a Rabbit Polyclonal antibody against Arfgap With Gtpase Domain, Ankyrin Repeat And Ph Domain 2.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Arf-GAP With GTPase, ANK Repeat And PH Domain Containing Protein 2 (AGAP2) Immunogen: Human AGAP2. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q99490 |
| Gene ID | 116986 |
| NCBI Accession | NP_001116244.1, NM_001122772.2, NP_055585.1, NM_014770.3 |
| OMIM | 605476 |
| Alias | CENTG1,GGAP2,PIKE |
| Background | Antibody anti-AGAP2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
AGAP2, also known as PIKE-A, plays a key role in regulating cell survival, growth signaling pathways, and intracellular transport. It interacts with phosphoinositide 3-kinase (PI3K), enhancing PI3K-Akt signaling and promoting anti-apoptotic responses. AGAP2 contains a GTPase domain, ankyrin repeats, and a PH domain, enabling its participation in vesicle trafficking, cytoskeletal dynamics, and endosomal transport. It is expressed in neurons, where it supports synaptic stability and neuronal survival, and is overexpressed in cancers such as glioblastomas, driving tumor growth and resistance to apoptosis. AGAP2’s dual roles in neuronal plasticity and oncogenesis make it a significant target for therapeutic research.
Productos relacionados
Arf-GAP With GTPase, ANK Repeat And PH Domain Containing Protein 2 (AGAP2) Antibody
Rabbit Polyclonal against the AGAP2 protein.…
Ver producto Arf-GAP With GTPase, ANK Repeat And PH Domain Containing Protein 2 (AGAP2) Antibody
Arfgap With Gtpase Domain, Ankyrin Repeat And Ph Domain 2 Antibody is a Rabbit Polyclonal antibody against Arfgap With G…
Ver producto Arf-GAP With GTPase, ANK Repeat And PH Domain Containing Protein 2 (AGAP2) Antibody
AGAP2 Antibody is a Rabbit Polyclonal against AGAP2.…
Ver producto