Human Arf-GAP With Coiled-Coil, ANK Repeat And PH Domain Containing Protein 3 (ACAP3) ELISA Kit
715€ (96 tests)
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935106861
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name
Human Arf-GAP With Coiled-Coil, ANK Repeat And PH Domain Containing Protein 3 (ACAP3) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx385575
tested applications
ELISA
Description
Human Arf-GAP With Coiled-Coil, ANK Repeat And PH Domain Containing Protein 3 (ACAP3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Centaurin Beta 5 (CENTb5) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Arf-GAP With Coiled-Coil, ANK Repeat And PH Domain Containing Protein 3 (ACAP3) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.313 ng/ml - 20 ng/ml |
| Sensitivity | < 0.19 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q96P50 |
| Gene ID | 116983 |
| Alias | CENTB5,Centaurin beta 5 |
| Background | Elisa kits for ACAP3 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ACAP3 functions as a GTPase-activating protein for Arf6, a regulator of membrane trafficking and cytoskeletal dynamics. It contains a PH domain, ankyrin repeats, and coiled-coil motifs, facilitating its association with phosphoinositides and Arf proteins. ACAP3 regulates endocytic recycling and membrane ruffling, crucial for migration, polarity, and adhesion. Highly expressed in neurons and epithelial cells, it contributes to dendritic spine formation, synaptic plasticity, and epithelial remodeling. Dysregulation of ACAP3 has been linked to impaired neuronal development and cancer metastasis, highlighting its role in membrane dynamics and signaling critical for cellular function and adaptation.
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