Human Archaelysin Family Metallopeptidase 2 (AMZ2) ELISA Kit
715€ (96 tests)
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name
Human Archaelysin Family Metallopeptidase 2 (AMZ2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx385737
tested applications
ELISA
Description
Human Archaelysin Family Metallopeptidase 2 (AMZ2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Archaemetzincin 2 (AMZ2) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Archaelysin Family Metallopeptidase 2 (AMZ2) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.313 ng/ml - 20 ng/ml |
| Sensitivity | < 0.19 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q86W34 |
| Gene ID | 51321 |
| OMIM | 615169 |
| Alias | AMZ2 |
| Background | Elisa kits for AMZ2 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
AMZ2, like AMZ1, is a zinc-dependent metallopeptidase that functions in the regulation of protein degradation and extracellular matrix remodeling. AMZ2 is widely expressed in tissues, including those involved in immune responses and connective tissue maintenance. AMZ2 has been shown to play a role in proteolytic processes that modulate cellular signaling pathways, tissue repair, and organ development. Its enzymatic activity depends on zinc ions, which are essential for stabilizing the active site and facilitating substrate cleavage. AMZ2 is involved in regulating inflammatory processes by processing bioactive peptides and matrix proteins, contributing to tissue remodeling during immune responses and injury repair. Dysregulation of AMZ2 has been associated with chronic inflammation, cancer progression, and neurodegenerative diseases, where altered proteolytic activity can disrupt tissue integrity and cellular signaling. AMZ2 is emerging as a potential target for therapeutic interventions aimed at modulating protease activity in pathological conditions.
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