Human Apoptosis Antagonizing Transcription Factor (AATF) Protein

Este producto es parte de AATF - Apoptosis Antagonizing Transcription Factor
Human Apoptosis Antagonizing Transcription Factor (AATF) Protein

Pida mas información

935106861

info@markelab.com

Precio

221€ (10 µg)

Protein AATF

proveedor

Abbexa

reference

abx168127

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Apoptosis Antagonizing Transcription Factor Protein is a recombinant Human protein expressed in E. coli.


Background

AATF (Apoptosis Antagonizing Transcription Factor), also known as Che-1, is a transcription factor involved in various cellular processes, including the regulation of apoptosis, cell cycle progression, and DNA damage response. It acts as a survival factor by inhibiting apoptotic pathways and promoting cell proliferation and survival.It also interacts directly with nuclear hormone receptors to enhance their transactivation. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis

Características del producto

category

Proteins and Peptides


origin

Human


host

E. coli


immunogen target

Apoptosis Antagonizing Transcription Factor (AATF)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 56.1 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ser273-Ser477 Tag: N-terminal His tag and GST tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

AATF


dry ice

No


availability

Shipped within 5-7 working days.


alias

DED,BFR2,CHE1,CHE-1


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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