Human Apoptosis Antagonizing Transcription Factor (AATF) Protein
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935106861
info@markelab.com
Precio
221€ (10 µg)
Protein AATF
proveedor
Abbexareference
abx168127Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Apoptosis Antagonizing Transcription Factor Protein is a recombinant Human protein expressed in E. coli.
Background
AATF (Apoptosis Antagonizing Transcription Factor), also known as Che-1, is a transcription factor involved in various cellular processes, including the regulation of apoptosis, cell cycle progression, and DNA damage response. It acts as a survival factor by inhibiting apoptotic pathways and promoting cell proliferation and survival.It also interacts directly with nuclear hormone receptors to enhance their transactivation. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
Apoptosis Antagonizing Transcription Factor (AATF)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 56.1 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ser273-Ser477 Tag: N-terminal His tag and GST tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
AATF
dry ice
No
availability
Shipped within 5-7 working days.
alias
DED,BFR2,CHE1,CHE-1
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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proveedor
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