Apoptosis Antagonizing Transcription Factor (AATF) Antibody
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935106861
info@markelab.com
Precio
52€ (10 µg)
Antibody anti-AATF
proveedor
Abbexareference
abx013816Tested Applications
ELISA, WBreactivity
Human, Mouse, Ratstatus
RUOclonality
PolyclonalDescripción
Rabbit polyclonal antibody against AATF protein. Immunogen region is N-terminal.
Background
AATF (Apoptosis Antagonizing Transcription Factor), also known as Che-1, is a transcription factor involved in various cellular processes, including the regulation of apoptosis, cell cycle progression, and DNA damage response. It acts as a survival factor by inhibiting apoptotic pathways and promoting cell proliferation and survival.It also interacts directly with nuclear hormone receptors to enhance their transactivation. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human, Mouse, Rat
immunogen target
Apoptosis Antagonizing Transcription Factor (AATF)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB
purification
Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
recommended dilution
WB: 1/500 - 1/3000, ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol.
size 1
10 µg
size 2
100 µg
size 3
200 µg
size 4
300 µg
size 5
1 mg
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
AATF
dry ice
No
availability
Shipped within 5-10 working days.
alias
DED,BFR2,CHE1,CHE-1
uniprot id
note
Concentration: 1 mg/ml -
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