Human Apolipoprotein O (APOO) CLIA Kit
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Human Apolipoprotein O (APOO) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Serum, plasma, tissue homogenates and other biological fluids.
Documents del producto
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Apolipoprotein O (APOO) |
| Reactivity | Human |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.054 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Serum, plasma, tissue homogenates and other biological fluids. |
| Availability | Shipped within 5-20 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | MIC26,MICOS26,FAM121B,My025,MIC23,Apolipoprotein O |
| Background | CLIA Kits APOO |
| Status | RUO |
| Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Apolipoprotein O (APOO) is a lipid-associated protein that is primarily involved in lipid metabolism, mitochondrial function, and cardiovascular health. APOO is widely expressed in the heart, liver, skeletal muscle, and adipose tissues, where it associates with circulating lipoproteins such as high-density lipoproteins (HDL) and very-low-density lipoproteins (VLDL). APOO plays a critical role in modulating mitochondrial function and energy metabolism by influencing mitochondrial membrane integrity and regulating reactive oxygen species (ROS) production. Additionally, APOO has been implicated in the formation and secretion of lipoproteins, as well as the trafficking of cholesterol and triglycerides. Altered APOO expression has been observed in metabolic and cardiovascular diseases, including obesity, insulin resistance, and atherosclerosis, where it contributes to lipid accumulation, mitochondrial dysfunction, and oxidative stress. Recent findings suggest APOO may also play a role in regulating cellular responses to hypoxia and energy stress, highlighting its importance in maintaining cellular and mitochondrial homeostasis. As a key mediator of lipid metabolism and mitochondrial function, APOO is an emerging target for research into the prevention and treatment of metabolic disorders, cardiovascular diseases, and oxidative stress-related conditions. Further investigation is needed to fully elucidate APOO’s mechanisms and therapeutic potential in lipid homeostasis and mitochondrial health.
Related Products
Apolipoprotein O (APOO) Antibody
ApoO: apolipoprotein O, also known as MYO25, FAM121B, MGC4825. Entrez Protein NP077027. It is a chrondroitin-sulfate chain containing member of the apolipoprotein family and is an original glycoprotein up-regulated by diabetes in human Heart. Promotes cholesterol efflux from macrophage cells. Detected in HDL, LDL and VLDL. Secreted by a microsomal triglyceride transfer protein (MTTP)-dependent mechanism, probably as a VLDL-associated protein that is subsequently transferred to HDL. May be involved in myocardium-protective mechanisms against lipid accumulation.
Ver Producto
Apolipoprotein O (APOO) Antibody
This gene is a member of the apolipoprotein family. Members of this protein family are involved in the transport and metabolism of lipids. The encoded protein associates with HDL, LDL and VLDL lipoproteins and is characterized by chondroitin-sulfate glycosylation. This protein may be involved in preventing lipid accumulation in the myocardium in obese and diabetic patients. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 4, 5, 12 and 16.
Ver Producto
Apolipoprotein O (APOO) Antibody
Apolipoprotein O Antibody is a Rabbit Polyclonal against Apolipoprotein O.
Ver Producto