Human Apolipoprotein A2 (APOA2) Protein

Este producto es parte de APOA2 - Apolipoprotein A2
Human Apolipoprotein A2 (APOA2) Protein

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935106861

info@markelab.com

Precio

208€ (10 µg)

Protein APOA2

proveedor

Abbexa

reference

abx065403

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Human Apolipoprotein A2 (APOA2) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).


Background

APOA2 is the second most abundant protein in HDL particles and is involved in stabilizing HDL structure and influencing cholesterol metabolism. It plays a role in modulating HDL remodeling, impacting the balance between cholesterol efflux and lipid delivery. APOA2 has a controversial role in cardiovascular health, with studies showing both pro-atherogenic and anti-atherogenic effects depending on genetic variants and lipid context. Elevated APOA2 levels have been linked to obesity, insulin resistance, and metabolic syndrome, while deficiencies can impair HDL stability and function. APOA2 interacts with enzymes like hepatic lipase and proteins such as CETP (cholesteryl ester transfer protein), which regulate lipid exchange and metabolism. Its dual role in lipid homeostasis and metabolic health highlights its significance in cardiovascular disease and metabolic disorders.

Características del producto

category

Proteins and Peptides


origin

Human


host

E. coli


immunogen target

Apolipoprotein A2 (APOA2)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 10 mM PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in 10 mM PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 22.4 kDa Observed MW (SDS-PAGE): 21 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Gln24-Gln100 Tag: N-terminal His tag and SUMO tag


expression

Recombinant


purity

> 90%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 5% Trehalose.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

APOA2


dry ice

No


availability

Shipped within 5-12 working days.


alias

APOA2, Apo-AII, ApoA-II, apoAII, Apolipoprotein A2,APO A2,APO-A2,Apolipoprotein A-II


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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