Apolipoprotein A-II (Apo AII) Antibody
1033.5€ (1 mg)
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Name
Apolipoprotein A-II (Apo AII) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx023222
Tested Applications
IEP
Description
Apo AII Antibody is a Goat polyclonal antibody for lipoproteins against Apo AII.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Apolipoprotein A-II (Apo AII) |
| Host | Goat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by affinity chromatography. |
| Size 1 | 1 mg |
| Form | Liquid |
| Tested Applications | IEP |
| Buffer | Buffer contains NaN3 as a preservative. |
| Availability | Shipped within 10-20 working days. |
| Storage | Aliquot and store at 2°C to 8°C upon receipt. |
| Dry Ice | No |
| Alias | APOA2, Apo-AII, ApoA-II, apoAII, Apolipoprotein A2,APO A2,APO-A2,Apolipoprotein A-II |
| Background | Antibody anti-APOA2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
APOA2 is the second most abundant protein in HDL particles and is involved in stabilizing HDL structure and influencing cholesterol metabolism. It plays a role in modulating HDL remodeling, impacting the balance between cholesterol efflux and lipid delivery. APOA2 has a controversial role in cardiovascular health, with studies showing both pro-atherogenic and anti-atherogenic effects depending on genetic variants and lipid context. Elevated APOA2 levels have been linked to obesity, insulin resistance, and metabolic syndrome, while deficiencies can impair HDL stability and function. APOA2 interacts with enzymes like hepatic lipase and proteins such as CETP (cholesteryl ester transfer protein), which regulate lipid exchange and metabolism. Its dual role in lipid homeostasis and metabolic health highlights its significance in cardiovascular disease and metabolic disorders.