Human Apolipoprotein A-II (APOA2) CLIA Kit

845€ (96 tests)
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935106861
info@markelab.com
name
Human Apolipoprotein A-II (APOA2) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx491747
tested applications
CLIA
Description
Human Apolipoprotein A-II (APOA2) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Serum, plasma and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | CLIA Kits |
Immunogen Target | Apolipoprotein A-II (APOA2) |
Reactivity | Human |
Detection Method | Chemiluminescent |
Assay Data | Quantitative |
Assay Type | Sandwich |
Test Range | 1.56 ng/ml - 100 ng/ml |
Sensitivity | < 0.69 ng/ml |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Size 1 | 96 tests |
Size 2 | 5 × 96 tests |
Size 3 | 10 × 96 tests |
Form | Lyophilized |
Tested Applications | CLIA |
Sample Type | Serum, plasma and other biological fluids. |
Availability | Shipped within 5-20 working days. |
Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
Dry Ice | No |
Alias | APOA2, Apo-AII, ApoA-II, apoAII, Apolipoprotein A2,APO A2,APO-A2,Apolipoprotein A-II |
Background | CLIA Kits APOA2 |
Status | RUO |
Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
APOA2 is the second most abundant protein in HDL particles and is involved in stabilizing HDL structure and influencing cholesterol metabolism. It plays a role in modulating HDL remodeling, impacting the balance between cholesterol efflux and lipid delivery. APOA2 has a controversial role in cardiovascular health, with studies showing both pro-atherogenic and anti-atherogenic effects depending on genetic variants and lipid context. Elevated APOA2 levels have been linked to obesity, insulin resistance, and metabolic syndrome, while deficiencies can impair HDL stability and function. APOA2 interacts with enzymes like hepatic lipase and proteins such as CETP (cholesteryl ester transfer protein), which regulate lipid exchange and metabolism. Its dual role in lipid homeostasis and metabolic health highlights its significance in cardiovascular disease and metabolic disorders.
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