Human Anoctamin 6 (ANO6) CLIA Kit
845€ (96 tests)
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name
Human Anoctamin 6 (ANO6) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx495006
tested applications
CLIA
Description
Human Anoctamin 6 (ANO6) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Tissue homogenates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Anoctamin 6 (ANO6) |
| Reactivity | Human |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.312 ng/ml - 20 ng/ml |
| Sensitivity | < 0.127 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Tissue homogenates and other biological fluids. |
| Availability | Shipped within 5-20 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | ANO6,TMEM16F |
| Background | CLIA Kits ANO6 |
| Status | RUO |
| Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ANO6, also known as TMEM16F, is a dual-function protein acting as a calcium-activated phospholipid scramblase and ion channel. It plays a critical role in plasma membrane repair, cell death (apoptosis), and blood coagulation by regulating the externalization of phosphatidylserine (PS), a process essential for platelet activation and membrane remodeling. ANO6 is expressed in various tissues, including the hematopoietic system, skeletal muscle, and immune cells. Mutations in ANO6 cause Scott syndrome, a rare bleeding disorder characterized by impaired PS exposure on platelet surfaces, which disrupts proper blood clotting. ANO6 also contributes to cellular responses to mechanical stress, apoptosis, and bone development. Its roles in membrane repair and phospholipid scrambling underscore its importance in cell survival, homeostasis, and coagulation.
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