Human Anoctamin 2 (ANO2) Protein

Este producto es parte de ANO - Anoctamin
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221€ (10 µg)

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935106861
info@markelab.com
name
Human Anoctamin 2 (ANO2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx650130
tested applications
WB, SDS-PAGE

Description

Human ANO2 Protein is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
Anoctamin 2 (ANO2)
Host
E. coli
Origin
Human
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 24.4 kDa

Concentration: Prior to lyophilization: 200 µg/ml

Sequence Fragment: Ala823-Val1003

Tag: N-terminal His tag
Expression
Recombinant
Purity
> 90%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q9NQ90
Alias
ANO2,C12orf3,TMEM16B
Background
Protein ANO2
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

ANO2, or TMEM16B, is another calcium-activated chloride channel (CaCC) predominantly expressed in sensory neurons and olfactory tissues. ANO2 plays a vital role in olfactory transduction, where it contributes to the depolarization of sensory neurons in response to odorant stimulation. Beyond the olfactory system, ANO2 is involved in regulating neuronal excitability and signal transmission in the central nervous system, including brain regions related to sensory processing. Dysregulation of ANO2 function can impair sensory perception and may contribute to olfactory disorders and neurodegenerative conditions. Its precise role in ion homeostasis and neuronal signaling makes it an important target for understanding sensory transduction and related diseases.

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