Anoctamin-2 (ANO2) Antibody
312€ (60 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Anoctamin-2 (ANO2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx002656
tested applications
IF/ICC
Description
ANO2 Antibody is a Rabbit Polyclonal antibody against ANO2. ANO2 belongs to a family of calcium-activated chloride channels (CaCCs) (reviewed by Hartzell et al., 2009.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Anoctamin-2 (ANO2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | IF/ICC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9NQ90 |
| Gene ID | 57101 |
| NCBI Accession | NP_001265526.1 |
| Alias | ANO2,C12orf3,TMEM16B |
| Background | Antibody anti-ANO2 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
ANO2, or TMEM16B, is another calcium-activated chloride channel (CaCC) predominantly expressed in sensory neurons and olfactory tissues. ANO2 plays a vital role in olfactory transduction, where it contributes to the depolarization of sensory neurons in response to odorant stimulation. Beyond the olfactory system, ANO2 is involved in regulating neuronal excitability and signal transmission in the central nervous system, including brain regions related to sensory processing. Dysregulation of ANO2 function can impair sensory perception and may contribute to olfactory disorders and neurodegenerative conditions. Its precise role in ion homeostasis and neuronal signaling makes it an important target for understanding sensory transduction and related diseases.
Related Products
anti- ANO2 antibody
Calcium-activated chloride channel(CaCC) which may play a role in olfactory signal transduction. Odorant molecules bind to odor-sensing receptors(OSRs), leading to an increase in calcium entry that activates CaCC current which amplifies the depolarization of the OSR cells, ANO2 seems to be the underlying chloride channel involved in this process. May mediate light perception amplification in retina.
Ver Producto
Anoctamin-2 (ANO2) Antibody
ANO2 Antibody is a Rabbit Polyclonal antibody against ANO2. ANO2 belongs to a family of calcium-activated chloride channels (CaCCs) (reviewed by Hartzell et al., 2009.
Ver Producto
Anoctamin 2 (ANO2) Antibody
Anoctamin 2 Antibody is a Rabbit Polyclonal antibody against Anoctamin 2.
Ver Producto