Human Annexin A9 (ANXA9) Protein
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Description
Annexin A9 Protein is a recombinant Human protein expressed in E. coli.
Documents del producto
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Annexin A9 (ANXA9) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 68.4 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Met1-Met345 Tag: N-terminal His tag and GST tag |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | ANXA9,ANX31 |
| Background | Protein ANXA9 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
ANXA9 is a unique member of the annexin family characterized by its calcium-independent phospholipid-binding activity. Unlike other annexins, ANXA9 can interact with cell membranes without requiring calcium ions, suggesting distinct roles in membrane organization and signal transduction. ANXA9 is expressed in epithelial tissues and has been associated with keratinocyte differentiation and epithelial homeostasis, where it contributes to processes such as membrane repair and cell adhesion. Emerging evidence links ANXA9 to cancer progression, where altered expression correlates with epithelial-mesenchymal transition (EMT), a critical process in metastasis. Its calcium-independent function and role in epithelial cell regulation make it a unique regulator of membrane stability and cancer biology.
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