Annexin A9 (ANXA9) Antibody

Name: Annexin A9 (ANXA9) Antibody
Brand: Abbexa
SKU: abx029252
Price: 250 EUR
Availability: OnlineOnly

Este producto es parte de ANXA9 - Annexin A9

Pida mas información

935106861

info@markelab.com

Precio

250€ (80 µl)

Antibody anti-ANXA9

proveedor

Abbexa

reference

abx029252

Tested Applications

ELISA, WB

reactivity

Human

status

RUO

clonality

Polyclonal

Descripción

The annexins are a family of calcium-dependent phospholipid-binding proteins. Members of the annexin family contain 4 internal repeat domains, each of which includes a type II calcium-binding site. The calcium-binding sites are required for annexins to aggregate and cooperatively bind anionic phospholipids and extracellular matrix proteins. This gene encodes a divergent member of the annexin protein family in which all four homologous type II calcium-binding sites in the conserved tetrad core contain amino acid substitutions that ablate their function. However, structural analysis suggests that the conserved putative ion channel formed by the tetrad core is intact.

Background

ANXA9 is a unique member of the annexin family characterized by its calcium-independent phospholipid-binding activity. Unlike other annexins, ANXA9 can interact with cell membranes without requiring calcium ions, suggesting distinct roles in membrane organization and signal transduction. ANXA9 is expressed in epithelial tissues and has been associated with keratinocyte differentiation and epithelial homeostasis, where it contributes to processes such as membrane repair and cell adhesion. Emerging evidence links ANXA9 to cancer progression, where altered expression correlates with epithelial-mesenchymal transition (EMT), a critical process in metastasis. Its calcium-independent function and role in epithelial cell regulation make it a unique regulator of membrane stability and cancer biology.

Características del producto

clonality

Polyclonal

reactivity

Human

immunogen target

Annexin A9 (ANXA9)

host

Rabbit

conjugation

Unconjugated

form

Liquid

tested applications

ELISA, WB

purification

Purified through a protein A column, followed by peptide affinity purification.

buffer

PBS containing 0.09% sodium azide.

size 1

80 µl

size 2

400 µl

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

ANXA9

dry ice

availability

Shipped within 5-10 working days.

alias

ANXA9,ANX31

uniprot id

https://www.uniprot.org/uniprotkb/O76027

note

This product is for research use only.

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anti- ANXA9 antibody

proveedor

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reference

FNab00452

Tested Applications

ELISA, WB, IHC, IF

reactivity

human,mouse

status

RUO

clonality

polyclonal

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