Human Annexin A2 (ANXA2) Protein

Este producto es parte de ANXA2 - Annexin A2 (receptor)
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234€ (5 µg)

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935106861
info@markelab.com
name
Human Annexin A2 (ANXA2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx260570
tested applications
SDS-PAGE

Description

Human Annexin A2 (ANXA2) Protein is a recombinant protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Annexin A2 (ANXA2)
Host
E. coli
Origin
Human
Conjugation
Unconjugated
Observed MW
Molecular Weight: 42.8 kDa
Concentration: 0.5 mg/ml
Sequence Fragment: 1-339 AA.
Expression
Recombinant
Purity
> 95% (SDS-PAGE)
Purification
Purified from proprietary chomatographic techniques.
Size 1
5 µg
Size 2
20 µg
Size 3
1 mg
Form
Liquid
Tested Applications
SDS-PAGE
Buffer
20 mM Tris-HCl, pH 8.0, 0.1 M NaCl and 20% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Store at 4 °C if the entire vial will be used within 4 weeks. For long-term storage, store at -20 °C. For long-term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P07355
Alias
ANXA2,ANX2,ANX2L4,CAL1H
Background
Protein ANXA2
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

ANXA2 is a calcium-dependent phospholipid-binding protein involved in membrane organization, endocytosis, and exocytosis. It plays critical roles in actin cytoskeleton remodeling, facilitating cell adhesion, migration, and vesicular trafficking. ANXA2 is also implicated in angiogenesis and fibrinolysis by serving as a co-receptor for plasminogen and tissue plasminogen activator (tPA), promoting fibrin degradation. Overexpression of ANXA2 has been linked to cancer progression, particularly in breast, lung, and colorectal cancers, where it enhances tumor cell migration, invasion, and metastasis. Additionally, ANXA2 is associated with viral replication, particularly in influenza and hepatitis viruses, making it a therapeutic target for infectious diseases and cancers.
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