Human Annexin A2 (ANXA2) Protein

Este producto es parte de ANXA2 - Annexin A2 (receptor)
Human Annexin A2 (ANXA2) Protein

Pida mas información

935106861

info@markelab.com

Precio

221€ (10 µg)

Protein ANXA2

proveedor

Abbexa

reference

abx065365

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Recombinant Annexin A2 (ANXA2) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).


Background

ANXA2 is a calcium-dependent phospholipid-binding protein involved in membrane organization, endocytosis, and exocytosis. It plays critical roles in actin cytoskeleton remodeling, facilitating cell adhesion, migration, and vesicular trafficking. ANXA2 is also implicated in angiogenesis and fibrinolysis by serving as a co-receptor for plasminogen and tissue plasminogen activator (tPA), promoting fibrin degradation. Overexpression of ANXA2 has been linked to cancer progression, particularly in breast, lung, and colorectal cancers, where it enhances tumor cell migration, invasion, and metastasis. Additionally, ANXA2 is associated with viral replication, particularly in influenza and hepatitis viruses, making it a therapeutic target for infectious diseases and cancers.

Características del producto

category

Proteins and Peptides


origin

Human


host

E. coli


immunogen target

Annexin A2 (ANXA2)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 42.3 kDa Observed MW: 42 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Met1-Asp339 Tag: N-terminal His tag


expression

Recombinant


purity

> 97%


buffer

Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01%Sarcosyl, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

ANXA2


dry ice

No


availability

Shipped within 5-7 working days.


alias

ANXA2,ANX2,ANX2L4,CAL1H


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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