Human Ankyrin Repeat Domain-containing Protein 12 (ANKRD12) ELISA Kit

Background

ANKRD12 is a nuclear protein containing multiple ankyrin repeat domains that mediate protein-protein interactions, particularly in transcriptional regulation and signaling pathways. ANKRD12 has been shown to interact with nuclear factor-kappa B (NF-κB) signaling components, influencing inflammatory responses, apoptosis, and immune regulation. It also participates in modulating transcription factor activity and chromatin organization, affecting gene expression patterns during development and cellular stress responses. Emerging studies suggest that ANKRD12 is involved in tumorigenesis, where its dysregulation promotes aberrant cell proliferation and survival. ANKRD12’s role as a transcriptional co-regulator and its interaction with key signaling pathways position it as an important factor in both normal cellular function and disease progression, including cancer and inflammatory disorders.