Human Androgen Receptor (AR) CLIA Kit

Este producto es parte de AR - androgen receptor
Human Androgen Receptor (AR) CLIA Kit

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935106861

info@markelab.com

Precio

812.5€ (96 tests)

CLIA Kits AR

proveedor

Abbexa

reference

abx492549

Tested Applications

CLIA

reactivity

Human

status

RUO

clonality

Descripción

Human Androgen Receptor (AR) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Tissue homogenates, cell lysates and other biological fluids.


Human Androgen Receptor (AR) CLIA Kit es un kit CLIA tipo Sandwich para su uso con homogenizados de tejido, lisados celulares y otros fluidos biológicos.


Background

Androgen receptor (AR) is a nuclear receptor that mediates the effects of androgens, the male sex hormones, by regulating gene expression AR plays a critical role in the development and maintenance of male sexual characteristics, as well as in the regulation of muscle mass, bone density, and red blood cell production It functions by binding to androgen hormones, such as testosterone, and translocating into the nucleus, where it interacts with DNA to regulate the transcription of target genes involved in cell growth, differentiation, and metabolism AR is essential for normal male development, including the formation of the male reproductive organs and secondary sexual characteristics During adulthood, AR helps maintain prostate function, muscle mass, and bone density Mutations in the AR gene can lead to a variety of disorders, including androgen insensitivity syndrome, prostate cancer, and certain types of hair loss, where abnormal AR signaling contributes to disease development AR is also a therapeutic target for androgen-related diseases, including prostate cancer, where therapies aim to block or modulate AR activity

Características del producto

category

CLIA Kits


immunogen target

Androgen Receptor (AR)


reactivity

Human


test range

0.312 ng/ml - 20 ng/ml


sensitivity

< 0.113 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Chemiluminescent


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

KD,AIS,AR8,TFM,DHTR,SBMA,HYSP1,NR3C4,SMAX1,HUMARA,Dihydrotestosterone receptor,Nuclear receptor subfamily 3 group C member 4


storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit


or code

AR


dry ice

No


note

El rango y la sensibilidad pueden variar. Le recomendamos contactar con nosotros a fin de obtener la última información sobre posibles actualizaciones, que no estén representadas en este catalogo. Si necesita un rango específico, contáctenos y trataremos de ayudarle. Consulte sobre posible información que pueda ayudarle a elegir la dilución apropiada para sus muestras. Los kits CLIA están optimizados para la detección de muestras nativas, las proteínas recombinantes, pueden resultar problemáticas a causa de diferencias en la secuencia o cambios en la estructura terciaria.


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