Human Androgen Receptor (AR) CLIA Kit
643.5€ (96 tests)
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name
Human Androgen Receptor (AR) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx196434
tested applications
CLIA
Description
Human Androgen Receptor (AR) Chemiluminescent Immunoassay (CLIA) Kit is a Chemiluminescent Immunoassay (CLIA) kit against Androgen Receptor (AR).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Androgen Receptor (AR) |
| Reactivity | Human |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 78 pg/ml - 5000 pg/ml |
| Sensitivity | 46.9 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Serum, plasma and other biological fluids. |
| Availability | Shipped within 5-12 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | KD,AIS,AR8,TFM,DHTR,SBMA,HYSP1,NR3C4,SMAX1,HUMARA,Dihydrotestosterone receptor,Nuclear receptor subfamily 3 group C member 4 |
| Background | CLIA Kits AR |
| Status | RUO |
| Note | The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Androgen receptor (AR) is a nuclear receptor that mediates the effects of androgens, the male sex hormones, by regulating gene expression AR plays a critical role in the development and maintenance of male sexual characteristics, as well as in the regulation of muscle mass, bone density, and red blood cell production It functions by binding to androgen hormones, such as testosterone, and translocating into the nucleus, where it interacts with DNA to regulate the transcription of target genes involved in cell growth, differentiation, and metabolism AR is essential for normal male development, including the formation of the male reproductive organs and secondary sexual characteristics During adulthood, AR helps maintain prostate function, muscle mass, and bone density Mutations in the AR gene can lead to a variety of disorders, including androgen insensitivity syndrome, prostate cancer, and certain types of hair loss, where abnormal AR signaling contributes to disease development AR is also a therapeutic target for androgen-related diseases, including prostate cancer, where therapies aim to block or modulate AR activity
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