Human Anaphase-promoting complex subunit 16 (ANAPC16) ELISA Kit

Name: Human Anaphase-promoting complex subunit 16 (ANAPC16) ELISA Kit
Brand: Abbexa
SKU: abx502116
Price: 715 EUR
Availability: OnlineOnly

Este producto es parte de ANAPC - Anaphase-promoting complex subunit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for ANAPC16

proveedor

Abbexa

reference

abx502116

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Anaphase-promoting complex subunit 16 (ANAPC16) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Anaphase-promoting complex subunit 16 (ANAPC16) concentrations in tissue homogenates, cell lysates and other biological fluids.

Background

ANAPC16 is a structural and functional subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), where it contributes to the stability and assembly of the complex. ANAPC16 interacts with other core subunits to provide a scaffold for the APC/C, supporting its function as a critical E3 ubiquitin ligase during mitosis. It is involved in the targeting and ubiquitination of key regulators, including cyclin B, securin, and other proteins required for chromosome segregation and mitotic exit. ANAPC16 ensures proper APC/C activation and substrate recruitment, maintaining the progression of the cell cycle. Disruption or mutation of ANAPC16 leads to mitotic defects, genomic instability, and impaired cell proliferation, which are hallmarks of cancer development. ANAPC16’s role as a structural stabilizer underscores its importance in APC/C-mediated proteolysis and cell cycle progression.

Características del producto

immunogen target

Anaphase-promoting complex subunit 16 (ANAPC16)

reactivity

Human

test range

0.156 ng/ml - 10 ng/ml

assay data

Quantitative

form

Lyophilized

detection method

Colorimetric

sample type

Tissue homogenates, cell lysates and other biological fluids.

size 1

96 tests

alias

ANAPC16,C10orf104,CENP-27,Cyclosome subunit 16,APC16

storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.

or code

ANAPC16

dry ice

uniprot id

https://www.uniprot.org/uniprotkb/Q96DE5

note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

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Anaphase-Promoting Complex Subunit 16 (ANAPC16) Antibody

proveedor

Abbexa

reference

abx038290

Tested Applications

ELISA, WB

reactivity

Human

status

RUO

clonality

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