Human Anaphase-promoting complex subunit 16 (ANAPC16) ELISA Kit
715€ (96 tests)
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935106861
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name
Human Anaphase-promoting complex subunit 16 (ANAPC16) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx502116
tested applications
ELISA
Description
Human Anaphase-promoting complex subunit 16 (ANAPC16) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Anaphase-promoting complex subunit 16 (ANAPC16) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Anaphase-promoting complex subunit 16 (ANAPC16) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q96DE5 |
| OMIM | 613427 |
| Alias | ANAPC16,C10orf104,CENP-27,Cyclosome subunit 16,APC16 |
| Background | Elisa kits for ANAPC16 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ANAPC16 is a structural and functional subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), where it contributes to the stability and assembly of the complex. ANAPC16 interacts with other core subunits to provide a scaffold for the APC/C, supporting its function as a critical E3 ubiquitin ligase during mitosis. It is involved in the targeting and ubiquitination of key regulators, including cyclin B, securin, and other proteins required for chromosome segregation and mitotic exit. ANAPC16 ensures proper APC/C activation and substrate recruitment, maintaining the progression of the cell cycle. Disruption or mutation of ANAPC16 leads to mitotic defects, genomic instability, and impaired cell proliferation, which are hallmarks of cancer development. ANAPC16’s role as a structural stabilizer underscores its importance in APC/C-mediated proteolysis and cell cycle progression.
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