Human Amyloid Beta Precursor Protein Binding B1 Interacting Protein (APBB1IP) Protein

221€ (10 µg)
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935106861
info@markelab.com
name
Human Amyloid Beta Precursor Protein Binding B1 Interacting Protein (APBB1IP) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx166079
tested applications
WB, SDS-PAGE
Description
Amyloid Beta Precursor Protein Binding B1 Interacting Protein is a recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Proteins and Peptides |
Immunogen Target | Amyloid Beta Precursor Protein Binding B1 Interacting Protein (APBB1IP) |
Host | E. coli |
Origin | Human |
Conjugation | Unconjugated |
Observed MW | Molecular Weight: Calculated MW: 57.9 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ser188-Lys421 Tag: N-terminal His tag and GST tag |
Expression | Recombinant |
Purity | > 95% |
Size 1 | 10 µg |
Size 2 | 50 µg |
Size 3 | 100 µg |
Size 4 | 200 µg |
Size 5 | 500 µg |
Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
Tested Applications | WB, SDS-PAGE |
Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
Availability | Shipped within 5-7 working days. |
Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q9Y2B4 |
Alias | APBB1IP, INAG1, PREL1, RARP1, RIAM,Rap1-GTP-interacting adapter molecule |
Background | Protein APBB1IP |
Status | RUO |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
APBB1IP, also known as the Amyloid Beta A4 Precursor Protein-Binding Family B Member 1-Interacting Protein, is a protein involved in cellular signaling, particularly in processes that affect neuronal function. It is known for its role in interacting with amyloid precursor protein (APP), which is associated with Alzheimer’s disease. APBB1IP forms complexes with APP and other signaling proteins, participating in various pathways such as endocytosis, intracellular signaling, and possibly synaptic function. It has been shown to influence processes involved in synaptic plasticity, which are critical for memory and learning. Research into APBB1IP has helped improve our understanding of the molecular mechanisms underlying neurodegenerative diseases, and it is a target of interest in studies aiming to find therapeutic approaches for Alzheimer's disease and related disorders.
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