Family main features
APBB1IP, also known as Rap1-GTP-interacting adapter molecule (RIAM), is a crucial protein involved in integrin activation and signal transduction pathways. It belongs to the MRL (Mig-10/RIAM/Lamellipodin) family of adaptor proteins, which play significant roles in cell migration and adhesion. The protein is expressed in various tissues, particularly in hematopoietic cells, and is vital for the proper functioning of the immune system. APBB1IP facilitates the linkage between Ras-related protein 1 (Rap1) and integrins, which are essential for the regulation of cell adhesion and migration. This protein is implicated in various physiological processes, including immune cell trafficking, platelet aggregation, and cardiovascular homeostasis.
APBB1IP is composed of several key domains that facilitate its function:
APBB1IP is classified within the MRL family of proteins, which are characterized by their roles in cellular migration and adhesion. There are no well-defined subtypes of APBB1IP itself, but it shares functional similarities with other MRL family members, such as Lamellipodin and Mig-10, which also participate in actin cytoskeleton remodeling and cell migration.
APBB1IP is integral to several cellular functions:
Dysfunction or altered expression of APBB1IP is linked to various clinical conditions:
APBB1IP is a critical adaptor protein that facilitates integrin activation and cell migration by linking Rap1-GTP to downstream signaling pathways. Its structural domains enable it to interact with various proteins and phospholipids, playing essential roles in immune responses, platelet aggregation, and cell motility. Dysregulation of APBB1IP is associated with several diseases, including immune disorders, cardiovascular diseases, and cancer. Understanding the function and regulation of APBB1IP can provide insights into potential therapeutic targets for these conditions.
Amyloid Beta A4 Precursor Protein-Binding Family B Member 1-Interacting Protein (APBB1IP)
APBB1IP, INAG1, PREL1, RARP1, RIAM,Rap1-GTP-interacting adapter molecule
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Proteins and Peptides, Primary Antibodies, ELISA Kits) relacionados con APBB1IP - Amyloid beta A4 precursor protein-binding family B member 1-interacting protein
Se muestran ordenados por categorías para poder comparar cómodamente sus características principales. Esta tabla, que contiene un enlace con la ficha de cada producto, es exportable a Excel.
Esta página contiene 11 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | APBB1IP | abx500392 | Human Amyloid beta A4 precursor protein-binding family B member 1-interacting protein (APBB1IP) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q7Z5R6 | RUO | ||
Abbexa | APBB1IP | abx500393 | Mouse Amyloid beta A4 precursor protein-binding family B member 1-interacting protein (APBB1IP) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q8R5A3 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FineTest | APBB1IP | FNab07291 | anti- RIAM antibody | human | polyclonal | Rabbit | amyloid beta(A4) precursor protein-binding, family B, member 1 interacting protein | IgG | Unconjugated | ELISA, WB, IHC, IP | 100µg | Q7Z5R6 | RUO | |
Abbexa | APBB1IP | abx224113 | Amyloid Beta A4 Precursor Protein-Binding Family B Member 1-Interacting Protein (APBB1IP) Antibody | Human | Monoclonal | Mouse | Amyloid Beta A4 Precursor Protein-Binding Family B Member 1-Interacting Protein (APBB1IP) | ELISA, IHC, FCM | 362.5 | 100 µl | Q7Z5R6 | RUO | ||
Abbexa | APBB1IP | abx016129 | Amyloid Beta A4 Precursor Protein-Binding Family B Member 1-Interacting Protein (APBB1IP) Antibody | Human | Monoclonal | Mouse | Amyloid Beta A4 Precursor Protein-Binding Family B Member 1-Interacting Protein (APBB1IP) | Unconjugated | ELISA, FCM | 362.5 | 100 µl | Q7Z5R6 | RUO | |
Abbexa | APBB1IP | abx128126 | Amyloid Beta Precursor Protein Binding B1 Interacting Protein (APBB1IP) Antibody | Human | Polyclonal | Rabbit | Amyloid Beta Precursor Protein Binding B1 Interacting Protein (APBB1IP) | Unconjugated | WB, IHC, IF/ICC | 287.5 | 100 µl | RUO | ||
Abbexa | APBB1IP | abx323464 | Amyloid Beta Precursor Protein Binding Family B Member 1 Interacting Protein (APBB1IP) Antibody | Human | Polyclonal | Rabbit | Amyloid Beta Precursor Protein Binding Family B Member 1 Interacting Protein (APBB1IP) | Unconjugated | ELISA, WB | 187.5 | 50 µg | Q7Z5R6 | RUO | |
Abbexa | APBB1IP | abx237291 | Amyloid Beta A4 Precursor Protein-Binding Family B Member 1-Interacting Protein (APBB1IP) Antibody | Human | Polyclonal | Rabbit | Amyloid Beta A4 Precursor Protein-Binding Family B Member 1-Interacting Protein (APBB1IP) | Unconjugated | ELISA, WB, IHC, IP | 350 | 100 µg | Q7Z5R6 | RUO | |
Abbexa | APBB1IP | abx110957 | Amyloid Beta A4 Precursor Protein-Binding Family B Member 1-Interacting Protein (APBB1IP) Antibody | Human | Polyclonal | Rabbit | Amyloid Beta A4 Precursor Protein-Binding Family B Member 1-Interacting Protein (APBB1IP) | Unconjugated | ELISA, WB, IHC | 612.5 | 100 µl | Q7Z5R6 | RUO | |
Abbexa | APBB1IP | abx322718 | Amyloid Beta A4 Precursor Protein-Binding Family B Member 1-Interacting Protein (APBB1IP) Antibody | Human | Polyclonal | Rabbit | Amyloid Beta A4 Precursor Protein-Binding Family B Member 1-Interacting Protein (APBB1IP) | Unconjugated | ELISA, WB, IHC | 237.5 | 50 µl | Q7Z5R6 | RUO |
provider | Code | reference | name | origin | expression | host | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | APBB1IP | abx166079 | Human Amyloid Beta Precursor Protein Binding B1 Interacting Protein (APBB1IP) Protein | Human | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 212.5 | 10 µg | Q9Y2B4 | RUO |
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