Human Ameloblastin (AMBN) Protein
338€ (10 µg)
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name
Human Ameloblastin (AMBN) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx690708
tested applications
SDS-PAGE
Description
Ameloblastin (AMBN) protein is a recombinant Human protein expressed in HEK293 cells.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Ameloblastin (AMBN) |
| Host | HEK293 cells |
| Assay Type | Activity: Not tested Sequence Fragment: Val27-Pro447 Tag: C-terminal 6 His tag |
| Origin | Human |
| Observed MW | Calculated MW: 46.4 kDa Observed MW (SDS-PAGE): 60-80 kDa |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Purification | 0.2 µm filtered prior to lyophilization. |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | Prior to lyophilization: 20 mM PBS,150 mM NaCl,pH 7.4, containing 5%-8% Trehalose, Mannitol and 0.01% Tween 80. |
| Availability | Shipped within 5-15 working days. |
| Storage | Storage: Store lyophilized between -20 °C and -80°C. Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months. Shelf Life: 12 months. |
| Dry Ice | No |
| UniProt ID | Q9NP70 |
| Gene ID | 258 |
| OMIM | 601259, 616270 |
| Alias | AMBN |
| Background | Protein AMBN |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Reconstitute in sterile H2O to prepare a stock solution of concentration 0.25 mg/ml. Do not vortex. Endotoxin Level: < 1.0 EU per µg (LAL method). |
Descripción
Ameloblastin, encoded by the AMBN gene, is a protein primarily found in the extracellular matrix of dental tissues, particularly in enamel-forming cells called ameloblasts. It is a major component of the enamel matrix, which is essential for the formation and mineralization of dental enamel, the outer layer of teeth. Ameloblastin plays several important roles in tooth development and enamel formation. Matrix organization: Ameloblastin helps organize the enamel matrix, providing a scaffold for the deposition of mineral crystals during enamel formation. It interacts with other enamel matrix proteins and forms complexes that contribute to the structural integrity of the developing enamel. Mineralization regulation: Ameloblastin participates in the regulation of enamel mineralization by influencing the nucleation and growth of hydroxyapatite crystals, the main mineral component of enamel. It contains specific domains that can bind calcium and phosphate ions, which are essential for the mineralization process. Cell signaling: Ameloblastin can also act as a signaling molecule, influencing the behavior and function of ameloblasts during enamel development. It interacts with cell surface receptors and intracellular signaling pathways, modulating processes such as cell adhesion, proliferation, and differentiation.
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